In this QA Darrell S Pardi M D discusses the role that the microbiome plays in inflammatory bowel disease (IBD) and how this knowledge is guiding new approaches to treatment using fecal microbiota transplants and other microbiome replacement therapies Dr Pardi is a gastroenterologist at Mayo Clinic's campus in Rochester Minnesota whose research focuses on the clinical features Abundant and Diverse Fungal Microbiota in the Murine Intestine Autores: Michael McPherson Alexandra J Scupham Natasha Griffith Elizabeth Bent Laura L Presley Oluwadayo Oluwadara James Borneman Nagesh Rao Jonathan Braun Feilin Zhu

Fungi as Part of the Microbiota and Interactions With

Interestingly fungal and bacterial abundance in the gut appear to be negatively correlated and disruption of the bacterial microbiota is a prerequisite for fungal overgrowth The mechanisms behind bacterial colonization resistance are likely diverse including direct antagonism as well as bacterial stimulation of host defense mechanisms

Altered fungal microbiota biodiversity and composition in AS (A) The Venn diagram depicts OTUs that were unique to HC unique to AS or shared (B) Observed species and Shannon and Simpson indexes describing the alpha diversity of the fungal microbiota in two groups (C) ITS2/16S observed species ratio (D) Beta diversity

The olive fruit fly (OFF) Bactrocera oleae is the most devastating pest affecting olive fruit worldwide Previous investigations have addressed the fungal microbiome associated with olive drupes or B oleae but the impact of the insect on fungal communities of olive fruit remains undescribed In the present work the fungal microbiome of olive drupes infested and non-infested by the OFF

Although the primary fungal cultivars of these insects have been studied for decades comparatively little is known of their bacterial microbiota In this study we show that diverse fungus-growing insects are associated with a common bacterial community composed of the same dominant members

Fungal Microbiota Profile in Newly Diagnosed Treatment-nave Children with Crohn's Disease Fungal taxa significantly more abundant in CD stools including Cortinariaceae family [p = 0 02 The reduction of fungal diversity in CD stool in comparison with CD mucosa demonstrates the disturbance of the fungal community in CD children and

The diversity and abundance of fungi and bacteria on the

Dec 18 2019Introduction It is well accepted that the human body's resident microbiota play a critical role in the maintenance of human health with numerous studies demonstrating that alterations in microbial community composition are associated with disease states as diverse as irritable bowel syndrome acne periodontal diseases and atopic dermatitis [1–3]

One of the most striking results was that unlike bacterial microbiota the fungal microbiota was different between inflamed and non-inflamed mucosa in CD flare patients Fungi from the Xylariales order were more abundant on inflamed mucosa whereas Saccharomyces cerevisiae and Filobasidium uniguttulatum were more abundant in non-inflamed mucosa

Most metagenomic studies concur that although fungal diversity within an individual mycobiome is low both diversity and abundance of specific fungal lineages vary significantly from one individual to another (Parfrey et al 2011) These features are highly dependent on environmental factors individuals' demographics and medical history (immune status antimicrobials and other medications)

May 18 2020Endophytes colonize tissues of healthy host plants and play a crucial role in plant growth and development However little attention has been paid to the endophytes of tuber crops such as cassava which is used as a staple food by approximately 800 million people worldwide This study aimed to elucidate the diversity and composition of endophytic bacterial and fungal communities in different

The fungal microbiota were highly diverse Although Candida Aspergillus Cladosporium Hannaella and Wallemia spp were found to be the most abundant fungal microbiota no specific genera were associated with factory sealing time or fermentation products

Introduction and objective: Nosocomial invasive fungal infections particularly aspergillosis are an increasing problem in immunocompromised patients The presented study evaluates fungal diversity and the presence of Aspergillusin air samples from two hospitals Material and Methods: Over the course of one year (rainy and dry seasons) the air was sampled from three areas in two hospitals (1

Jun 06 2017Fungal infection results in dysbiosis of mosquito gut microbiota by significantly increasing gut bacterial loads and decreasing bacterial diversity In particular fungal infection causes overgrowth and translocation of the opportunistic pathogen Serratia marcescens from the gut to the hemocoel thus promoting mosquito death

The upper respiratory tract contains an abundant and diverse microbiota The nasal passages and sinuses are primarily colonized by members of the Firmicutes Actinobacteria and Proteobacteria The most common bacteria identified include Staphylococcus epidermidis viridans group streptococci (VGS) Corynebacterium spp (diphtheroids

Fungal Trans

A deeper analysis of the mycobiota taxonomic composition revealed 15 major fungal genera with Candida and Saccharomyces being the most abundant in both healthy donors and UC patients (Figures 1C S2C and S2D) Within the Candida genus Candida albicans was the most abundant and prevalent species (Figure S1F)

Dietary fat intake and shifts in gut bacterial community composition are associated with the development of obesity To date characterization of microbiota in lean versus obese subjects has been dominated by studies of gut bacteria Fungi recently shown to affect gut inflammation have received little study for their role in obesity We sought to determine the effects of high-fat diet on

To obtain full details of gut microbiota including bacteria fungi bacteriophages and helminths in giant pandas (GPs) we created a comprehensive microbial genome database and used metagenomic sequences to align against the database We delineated a detailed and different gut microbiota structures of GPs A total of 680 species of bacteria 198 fungi 185 bacteriophages and 45 helminths

On the other hand the large intestine (colon) contains a diverse and abundant microbiota that is important for normal function These microbes include Bacteriodetes (especially the genera Bacteroides and Prevotella) and Firmicutes (especially members of the genus Clostridium) Methanogenic archaea and some fungi are also present among many

A deeper analysis of the mycobiota taxonomic composition revealed 15 major fungal genera with Candida and Saccharomyces being the most abundant in both healthy donors and UC patients (Figures 1C S2C and S2D) Within the Candida genus Candida albicans was the most abundant and prevalent species (Figure S1F)